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no place for physicians to go to learn how to care for these kids,cheap jordans free shipping, essentially no hope because no one was taking any action."

The foundation swiftly raised awareness and funds for groundbreaking research, including the 2003 genetic study co-authored by Gordon and Collins.

"Once we found the gene mutation,www.amassdenver.com, we didn't have a treatment but we had hope," said Gordon, explaining how the gene defect, which causes a toxic buildup of the abnormal protein progerin, opened the door to treatments. "It didn't seem as unreachable anymore."

Gordon then teamed up with Kieran, who at the time was testing lonafarnib in pediatric cancer patients. The drug helps keep progerin out of the membranous walls of the nucleus -- the cellular control room that guards the body's DNA blueprint.

"Eventually the membrane gets so heavy that it collapses and the cell stops working," said Kieran,cheap jordans, explaining how progeria progressively kills the body's cells.

"The ability to repurpose a drug that was actually developed for cancer and turned out to have the right properties for this aging disease was key," said Collins of the quick transition from bench science to bedside treatments. "If you can teach an old drug a new trick, you're a lot closer to the answer than if you're starting from scratch."

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